Miguel-Aliaga LabGut Signalling and Metabolism


Key publications

  • Hudry B, Khadayate S. and Miguel-Aliaga I (2016)

    The sexual identity of adult intestinal stem cells controls organ size and plasticity. Nature 530, 344–348.

  • Reiff T, Jacobson J, Cognigni P, Antonello Z, Ballesta E, Tan KJ, Yew JY, Dominguez M and Miguel-Aliaga I (2015)

    Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. eLife 4, e06930.

  • Linneweber GA, Jacobson J, Busch KE, Hudry B, Christov CP, Dormann D, Yuan M, Otani T, Knust E, de Bono M and Miguel-Aliaga I (2014)

    Neuronal control of metabolism through nutrient-dependent modulation of tracheal branching. Cell 156, 69-83.

  • Lemaitre B and Miguel-Aliaga I (2013)

    The Digestive Tract of Drosophila melanogaster. Annual Review of Genetics 47, 377-404.

  • Talsma A, Christov CP, Terriente-Felix A, Linneweber G, Perea D, Wayland M, Shafer OT and Miguel-Aliaga I (2012)

    Remote control of renal function by the intestinal neuropeptide pigment-dispersing factor in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 109, 12177-12182.

  • Cognigni P, Bailey AP and Miguel-Aliaga I (2011)

    Enteric neurons and systemic signals couple nutritional and reproductive state with intestinal homeostasis. Cell Metabolism 13, 92-104.

Other publications

  • Soba P, Han C, Zheng Y, Perea D, Miguel-Aliaga I, Jan LY and Jan YN (2015)

    The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. eLife 4, e05491.

  • Wayland MT, Defaye A, Rocha J, Jayaram SA, Royet J, Miguel-Aliaga I, Leulier F and Cognigni P (2014)

    Spotting the differences: Probing host/microbiota interactions with a dedicated software tool for the analysis of faecal outputs in Drosophila. Journal of insect physiology 69, 126-135.

  • Martorell O, Merlos-Suarez A, Campbell K, Barriga FM, Christov CP, Miguel-Aliaga I, Batlle E, Casanova J and Casali A (2014)

    Conserved mechanisms of tumorigenesis in the Drosophila adult midgut. PloS one 9, e88413.

  • Sarraf-Zadeh L, Christen S, Sauer U, Cognigni P, Miguel-Aliaga I, Stocker H, Kohler K and Hafen E (2013)

    Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions. Developmental biology 381, 97-106.

  • Miguel-Aliaga I (2012)

    Nerveless and gutsy: intestinal nutrient sensing from invertebrates to humans. Seminars in cell & developmental biology 23, 614-620.

  • Miguel-Aliaga I, Oliver B and Teleman AA (2012)

    The flies of Icarus: science with wings in Crete. EMBO reports 13, 945-947.

  • Oyallon J, Apitz H, Miguel-Aliaga I, Timofeev K, Ferreira L and Salecker I (2012)

    Regulation of locomotion and motoneuron trajectory selection and targeting by the Drosophila homolog of Olig family transcription factors. Developmental biology 369, 261-276.

  • Suska A, Miguel-Aliaga I and Thor S (2011)

    Segment-specific generation of Drosophila Capability neuropeptide neurons by multi-faceted Hox cues. Developmental biology 353, 72-80.

  • Pulver SR, Cognigni P, Denholm B, Fabre C, Gu WX, Linneweber G, Prieto-Godino L, Urbancic V, Zwart M and Miguel-Aliaga I (2011)

    Why flies? Inexpensive public engagement exercises to explain the value of basic biomedical research on Drosophila melanogaster. Advances in physiology education 35, 384-392.

  • Miguel-Aliaga I, Thor S and Gould AP (2008)

    Postmitotic specification of Drosophila insulinergic neurons from pioneer neurons. PLoS biology 6, e58.

  • Bardet PL, Kolaghar G, Mynett A, Miguel-Aliaga I, Briscoe J, Meier P and Vincent JP (2008)

    A fluorescent reporter of caspase activity for live imaging. Proceedings of the National Academy of Sciences of the United States of America 105, 13901-13905.

  • Miguel-Aliaga I and Thor S (2009)

    Programmed cell death in the nervous system--a programmed cell fate? Current opinion in neurobiology 19, 127-133.

  • Baumgardt M, Miguel-Aliaga I, Karlsson D, Ekman H and Thor S (2007)

    Specification of neuronal identities by feedforward combinatorial coding. PLoS Biology 5, e37.

  • Sheldon TJ, Miguel-Aliaga I, Gould AP, Taylor WR and Conklin D (2007)

    A novel family of single VWC-domain proteins in invertebrates. FEBS letters 581, 5268-5274.

  • Miguel-Aliaga I and Thor S (2004)

    Segment-specific Prevention of Pioneer Neuron Apoptosis by Cell-autonomous, Postmitotic Hox Gene Activity. Development 131, 6093-6105.

  • Miguel-Aliaga I, Allan DW and Thor S (2004)

    Independent Roles of the dachshund and eyes absent Genes in BMP Signaling, Pathfinding and Neuropeptidergic Cell Specification. Development 131, 5837-5848.

  • Allan DW, St Pierre SE, Miguel-Aliaga I and Thor S (2003)

    Specification of neuropeptide cell identity by the integration of retrograde BMP signaling and a combinatorial transcription factor code. Cell 113, 73-86.

  • Chan YB, Miguel-Aliaga I, Franks C, Thomas N, Trulzsch B, Sattelle DB, Davies KE and van den Heuvel M (2003)

    Neuromuscular defects in a Drosophila survival motor neuron gene mutant. Human molecular genetics 12, 1367-1376.

  • Vargas JD, Culetto E, Ponting CP, Miguel-Aliaga I, Davies KE and Sattelle DB (2002)

    Cloning and developmental expression analysis of ltd-1, the Caenorhabditis elegans homologue of the mouse kyphoscoliosis (ky) gene. Mechanisms of development 117, 289-292.

  • Miguel-Aliaga I, Chan YB, Davies KE and van den Heuvel M (2000)

    Disruption of SMN function by ectopic expression of the human SMN gene in Drosophila. FEBS Letters 486, 99-102.

  • Miguel-Aliaga I, Culetto E, Walker DS, Baylis HA, Sattelle DB and Davies KE (1999)

    The Caenorhabditis elegans orthologue of the human gene responsible for spinal muscular atrophy is a maternal product critical for germline maturation and embryonic viability. Human molecular genetics 8, 2133-2143.

  • Talbot K, Miguel-Aliaga I, Mohaghegh P, Ponting CP and Davies KE (1998)

    Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex. Human molecular genetics 7, 2149-2156.