About our research work
Internal organs are constantly exchanging signals, and can undergo profound anatomical and functional changes in response to them, even in fully developed organisms. Such organ plasticity results from a need to integrate and respond to both environmental information and internal state, and is key to maintaining homeostasis and driving adaptive changes. We are interested in understanding the mechanisms by which organs sense change and respond to it: the molecules, cellular events and physiological adaptations involved. The intestine and its neurons are a fantastic system with which to tackle these questions.